Overview

The Wayne State longitudinal data set (collected on 4T Bruker scanner, with Siemens user interface) for the Brain Aging in Detroit Longitudinal Study, comprises 200 healthy individuals. The overarching aim of the Brain Aging in Detroit Longitudinal Study, is understanding the mechanisms driving human brain changes over the adult lifespan, identifying the risk factors and protective influences that modify the rate of change, and elucidating the relationships between changes in brain properties and cognitive performance. All participants were screened at baseline via a health questionnaire for the following conditions: presence of cardiovascular, neurological, or psychiatric disease, use of centrally acting medications, the habit of having three or more alcoholic drinks per day, as well as being minimally high school educated, native English speakers.

All participants underwent cognitive testing, and although the composition of testing batteries varied across cohorts, some tests are common to all: Cattell Culture Fair Intelligence Test, various forms of multiple-choice vocabulary tests (Educational Testing Service), tests of episodic memory and working memory. Cognitive variables are available to qualified investigators upon request.

302 total anatomical scans (200 subjects at baseline x 2 sessions/subject x 1 T1 MPRAGE scan/session) over 2 waves of data collection. The number of participants (after attrition) per wave are as follows:

Click here (pdf) for scan parameters.

Experimental Protocol

Participants were instructed to remain still in the scanner, with eyes closed.

Data Release Download

Click here to get the demographics.

Click here to access the compressed Wayne State Study 11 dataset.

NITRC Download Instructions
In order to access the data, you must first register for an account with NITRC. After you have done so, click here to request access to the 1000 Functional Connectomes Project on NITRC. Users will be approved within 1 business day.

Personnel

Principal Investigator: Senior Personnel and Collaborators (Alphabetical order):

*please send correspondence to Naftali Raz (nraz@wayne.edu)

1Institute of Gerontology, Wayne State University, Detroit MI, USA
2Department of Psychology, Wayne State University, Detroit MI, USA
3Max Planck Institute for Human Development, Berlin, Germany
4Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit MI, USA

Data Sharing License

Creative Commons – Attribution-NonCommercial Share Alike (CC-BY-NC-SA): Standard INDI data sharing policy. Prohibits use of the data for commercial purposes.

Publications